Sidney Toler

Charlie Chan

Victor Sen Yung

Jimmy Chan

Cesar Romero

Fred Rhadini

Douglas Fowley

Peter Lewis

Pauline Moore

Eve Cairo

Donald MacBride

Deputy Police Chief J.J. Kilvaine

Douglass Dumbrille

Stewart Salsbury, alias Thomas Gregory

Trevor Bardette

Dr. Zodiac's Servant

Gerald Mohr

Dr. Zodiac (in disguise)

Wally Vernon

Elmer

June Gale

Myra Rhadini

Billie Seward

Mrs. Bessie Sibley